Histone H4, Full Length, His-tag Recombinant
Human Histone 4 (HIST2H4A) (GenBank Accession No. NM_003548), a.a. 2-103(end) with N-terminal His-tag, MW = 12.1 kDa, expressed in an E. coli expression system.
≥75%
1. Kornberg, R.D. (1977) Annu. Rev. Biochem., 46, 931-954.
2. van Holde, K.E. (1989) Chromatin, 1-497.
Application Reference(s):
1. Small Molecule Inhibitors of the Human Histone Lysine Methyltransferase NSD2 / WHSC1 / MMSET Identified from a Quantitative High-Throughput Screen with Nucleosome Substrate (2017)
2.Differential mode of antimicrobial actions of arginine-rich and lysine-rich histones against Gram-positive Staphylococcus aureus (2013)
3. Extracellular histones are essential effectors of C5aR- and C5L2-mediated tissue damage and inflammation in acute lung injury (2013)