Histone H3 (2-58), GST-tag

Catalog #: 52013
Size: 500 µg
$315
Species: Human
Host Species: E. coli
MW: 32 kDa
Genbank #: NM_003532
Tag(s): N-terminal GST-tag
a.a: 2–58
Description:
Human Histone 3 (GenBank Accession No. NM_003532), a.a. 2-58 with N-terminal GST-tag, MW = 32 kDa, expressed in an E. coli expression system.
UniProt
P68431
Synonym(s):
Histone 3.1, HIST1H3E
Formulation:
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 20% glycerol, and 3 mM DTT.
Format:
Aqueous buffer solution
Application(s):
Useful as a substrate for methyltransferases or acetyltransferases and for screening small molecular inhibitors of histone methyltransferases for drug discovery.
Reference(s):

1. Loyola, A. et al., Mol. Cell 24 (2), 309-316 (2006).
2. Groth, A. et al., Mol. Cell 17 (2), 301-311 (2005).

Application Reference(s):
Differential mode of antimicrobial actions of arginine-rich and lysine-rich histones against Gram-positive Staphylococcus aureus (2013)

Warning(s):
Avoid freeze/thaw cycles.
Scientific Category:
Methyltransferase
Product Type:
Substrate
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