Histone H1, Full Length, His-tag Recombinant

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Catalog #
52043
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Description

Recombinant human Histone H1, full length (amino acids 2-194). This construct contains a N-terminal His-tag (6xHis). The recombinant protein was affinity purified.

Synonyms
Histone H1, H1F0
Product Info
Storage and Usage
Citations
Species
Human
Construct
Histone H1 (His-2-194(end))
Host Species/Expression System
E. coli
Purity

≥90%

Format
Aqueous buffer solution
Formulation
8 mM phosphate pH 7.4, 110 mM NaCl, 2.2 mM KCl, 3 mM DTT, and 20% glycerol.
MW
22 kDa
Amino Acids
2–194(end)
Genbank #
NM_005318
UniProt #
P07305
Tag(s)
N-terminal His-tag
Background
Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation.