CD28H, Fc fusion, Biotin-labeled (Human) HiP™

Catalog #: 71239
Size: 50 µg
$405
Species: Human
Host Species: HEK293 cells
MW: 40 kDa
Genbank #: NM_144615
Tag(s): C-terminal Fc fusion (Human IgG1), C-terminal Avi-tag™
a.a: 23-128
Description:

Human CD28 homolog (CD28H), also known as Transmembrane and immunoglobulin domain-containing protein 2 (TMIGD2) and immunoglobulin and prolinerich receptor 1 (IGPR-1). GenBank Accession No. NM_144615, a.a. 23-128 fused at the C-terminus to the Fc portion of human IgG1 followed by a C-terminal AviTag™ expressed in a HEK293 expression system. MW = 40 kDa. This protein is enzymatically biotinylated using Avi-tag™ technology. Biotinylation is confirmed to be greater than 90%. This protein runs at a higher MW by SDS-PAGE due to glycosylation.

UniProt
P10747
Synonym(s):
CD28 homolog, Transmembrane and immunoglobulin domain-containing protein 2 TMIGD2, immunoglobulin and proline-rich receptor 1, IGPR-1
Formulation:
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol
Format:
Aqueous buffer solution
Storage / Stability:
At least 6 months at –80°C.
Application(s):
Useful for studying protein binding and for screening small molecules and antibodies.
Reference(s):
1. Zhu, Y., et al., Nat. Commun. 2013; 4:2043.
2. Zhu, Y., et al., J. Immunol. 2015; 194:142.2.
Notes:

HiP™ indicates a high purity protein with ≥90% purity as measured by gel filtration.

Warning(s):

Avoid freeze/thaw cycles. Protein may be diluted to ≥100 μg/ml in PBS + glycerol and stored at -80°C.

Scientific Category:
Immunotherapy
Product Type:
Recombinant Protein
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Product Datasheets

71239_Lot150901-G.pdf