CD137 (4-1BB), Fc Fusion, Biotin-labeled (Human) HiP™

Catalog #: 71171
Size: 50 µg
$405
Species: Human
Host Species: HEK293
MW: 45.9 kDa + glycans
Genbank #: NM_001561
Tag(s): C-terminal Fc fusion, Avi-Tag
a.a: 24-186
Description:

Human secreted CD137, Fc fusion protein, also known as Tumor Necrosis Factor Receptor Superfamily member 9, TNFRSF9, and ILA, GenBank Accession No. NM_001561, a.a. 24-186, expressed in a HEK293 cell expression system, fused at the C-terminus to the Fc portion of human IgG1 and enzymatically biotin-labeled using Avi-tag™ technology. MW = 45.9 kDa (monomer). Biotinylation is confirmed to be >90%. This protein runs at a higher MW by SDS-PAGE due to glycosylation.

UniProt
Q07011
Synonym(s):
Tumor Necrosis Factor Receptor Superfamily member 9, TNFRSF9, ILA
Endotoxin Level:
<1 EU/μg
Formulation:
8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol
Format:
Aqueous buffer solution
Storage / Stability:
At least 6 months at –80°C
Application(s):
Useful for studying protein binding and screening small molecules.
Reference(s):

1. Wilcox, R.A., et al., J. Clin. Invest. 2002; 109(5): 651-659.

2. Foell, J. et al., J. Clin. Invest. 2003; 111(10): 1505-1518.

Notes:

HiP™ indicates a high purity protein with ≥90% purity as measured by gel filtration.

Warning(s):
Avoid freeze/thaw cycles. Protein may be diluted to ≥ 100 μg/ml in PBS + glycerol and stored at -80°C.
Scientific Category:
Immunotherapy
Product Type:
Recombinant Protein
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Product Datasheets

71171_Lot150910.pdf