CD137 (4-1BB), Fc fusion (Human) HiP™

Catalog #: 71170
Size: 100 µg
$300
Species: Human
Host Species: HEK293
MW: 44 kDa
Genbank #: NM_001561
Tag(s): C-terminal Fc fusion (Human IgG1)
a.a: 24-186
Description:

Human secreted CD137, Fc fusion protein, also known as Tumor Necrosis Factor Receptor Superfamily member 9, TNFRSF9, and ILA, GenBank Accession No. NM_001561, a.a. 24-186 expressed in a HEK293 cell expression system. MW = 44 kDa (monomer). This protein runs at a higher MW by SDS-PAGE due to glycosylation.

UniProt
Q07011
Synonym(s):
Tumor Necrosis Factor Receptor Superfamily member 9, TNFRSF9, ILA
Endotoxin Level:
<1 EU/μg
Formulation:
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Format:
Aqueous buffer solution
Storage / Stability:
At least 6 months at –80°C
Application(s):
Useful for studying protein binding and screening small molecules.
Reference(s):

1. Wilcox, R.A., et al., J. Clin. Invest. 2002; 109(5): 651-659.

2. Foell, J. et al., J. Clin. Invest. 2003; 111(10): 1505-1518.

Notes:

HiP™ indicates a high purity protein with ≥90% purity as measured by gel filtration.

Warning(s):
Avoid freeze/thaw cycles. Protein may be diluted to ≥ 100 μg/ml in PBS + glycerol and stored at -80°C.
Scientific Category:
Immunotherapy
Product Type:
Recombinant Protein
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Product Datasheets

71170_Lot140520-D.pdf