B7-2 (CD86), Fc fusion, Biotin labeled (Human) HiP™

Catalog #: 71159
Size: 50 μg
$405
Species: Human
Host Species: HEK293
MW: 53.8 kDa+glycans
Genbank #: NM_006889
Tag(s): C-terminal Avi-tag™
a.a: 20-239
Description:

Human secreted B7-2, Fc fusion protein, also known as T-lymphocyte activation antigen CD86, B7.2, FUN-1, B70, BU63, and CD86. GenBank Accession No. NM_006889, a.a. 20-239 expressed in a HEK293 cell expression system. This protein is fused at the C-terminus to the Fc region of human IgG1 and is enzymatically biotinylated using Avi-tag™ technology. MW = 53.8 kDa (monomer). This protein runs at a higher MW by SDS-PAGE due to glycosylation.

UniProt
P42081
Synonym(s):
T-lymphocyte activation antigen CD86, B7.2, FUN-1, B70, BU63, CD86
Formulation:
8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol
Format:
Aqueous buffer solution
Storage / Stability:
At least 6 months at -80°C
Application(s):
Useful for studying protein binding and screening small molecules.
Reference(s):

1. Ertelt, J.M., et al. J. Leukocyte Biol. 2013; 94(2): 367-376.
2. Kuchroo, V.K., et al., Cell. 1995; 80(5):707-718.

Notes:

HiP™ indicates a high purity protein with ≥90% purity as measured by gel filtration.

This protein runs at a higher MW by SDS-PAGE due to glycosylation.

Warning(s):
Avoid freeze/thaw cycles. Protein may be diluted to  100 μg/ml in PBS + glycerol and stored at -80°C.
Scientific Category:
Immunotherapy
Product Type:
Fc Fusion Protein
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Product Datasheets

71159_Lot150417.pdf