HSP70, His-tag

Catalog #: 50287
Size: 200 µg
Species: Human
Host Species: E. coli
MW: 71 kDa
Genbank #: NM_005345
Tag(s): C-terminal His-tag
a.a: 2–641
In cooperation with other chaperones, Hsp70 stabilizes preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.
Human Heat Shock Protein 70 (GenBank Accession No. NM_005345), a.a. 2-641 with C-terminal His-tag, MW = 71 kDa, expressed in E. coli.
HSP70, Heat Shock Protein 70, DnaK, HSP70i
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 3 mM DTT, 20% glycerol, and 200 mM imidazole
Aqueous buffer solution
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
1. Lee K.J. et al., Exp. Mol. Med. 40 (6), 658-668 (2008).
2. Birtas-Atesoglu E. et al., Clin. Exp. Rheumatol. 26, S96-S98 (2008).
Avoid freeze/thaw cycles
Scientific Category:
Heat Shock Proteins
Product Type:
Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.

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