HDAC6, GST-Tag (HEK293-derived) Recombinant
Catalog #
100051
$440
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Description
Human HDAC6, a.a. 1-1215, N-terminal GST tag, GenBank Accession No. NM_006044, expressed in a HEK293 expression system. MW = 161 kDa.
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Synonyms
HDAC-6
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Product Data Gallery
Product Info
Storage and Usage
Citations
Species
Human
Host Species/Expression System
HEK293
Purity
≥65%
Formulation
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween20, 20% glycerol, 3mM DTT
MW
161 kDa
Amino Acids
1-1215
Specific Activity
10 pmol/min/µg
Genbank #
NM_006044
UniProt #
Q9UBN7
References
1. Li S. et al., Neurology. 41(2), 112-6 (2010).
2. Strausberg, R.L. et al., Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002).
Application References
1. Synthesis and biological evaluation of thiophene-based hydroxamate derivatives as HDACis with antitumor activities
2. Identification of HDAC6 selective inhibitors: pharmacophore based virtual screening, molecular docking and molecular dynamics simulation (2020)