GITRL, His-tag (Human)

Catalog #: 71190
Size: 100 µg
$310
Species: Human
Host Species: HEK293
MW: 17.1 kDa
Genbank #: NM_005092
Tag(s): N-terminal His-tag
a.a: 72-199
Description:

Human glucocorticoid-induced TNF-related ligand (GITRL), also known as AITRL, CD357L, or tumor necrosis factor ligand superfamily member 18 (TNFSF18). GenBank Accession No. NM_005092, a.a. 72-199 with an N-terminal His-tag, expressed in a HEK293 cell expression system. MW = 17.1 kDa. Note: this protein runs at a higher MW by SDSPAGE due to glycosylation.

UniProt
Q9UNG2
Synonym(s):
glucocorticoid-induced TNF-related ligand, AITRL, CD357L, tumor necrosis factor ligand superfamily member 18, TNFSF18
Endotoxin Level:
<1 EU/μg
Assay Conditions:
GITR-biotin binding to GITRL was confirmed using the GITRL: GITR Biotinylated] Inhibitor Screening Assay Kit (BPS Cat. #72061).
Formulation:
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol
Format:
Aqueous buffer solution
Storage / Stability:
>6 months at –80°C.
Application(s):
Useful for studying protein binding and for screening small molecules and antibodies.
Reference(s):
1. Shevach, E.M. et al., Nat. Rev. Immunol. 2006; 6: 613-618.
2. Hanabuchi, S. et al., Blood. 2006; 107(9): 3617-3623.

Notes:
The aggregation state of this product has been confirmed to be <10%.
Warning(s):
Avoid freeze/thaw cycles. Protein may be diluted to ≥ 100 μg/ml in PBS + glycerol and stored at -80°C.
Scientific Category:
Immunotherapy & Cytokines
Product Type:
Recombinant Proteins
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Product Datasheets

71190_Lot140826-D.pdf