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GITR (CD357), Fc Fusion, Biotin-labeled (Human) Recombinant

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Catalog #

71256

As low as $295 *

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Bulk/Custom

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Description

Human secreted GITR, also known as Glucocorticoid-induced TNFR-Related Protein, Tumor Necrosis Factor Receptor Superfamily member 18, TNFRSF18, Activation-Inducible TNFR Family Receptor, AITR, and CD357, GenBank Accession No. NM_004195, a.a. 26-161 expressed in a HEK293 cell expression system, fused at the C-terminus to the Fc portion of human IgG1, and enzymatically biotin-labeled using Avi-tag™ technology. MW = 43 kDa (monomer). This protein runs at a higher MW by SDS-PAGE due to glycosylation.

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Synonyms

Glucocorticoid-induced TNFR-Related Protein, Tumor Necrosis Factor Receptor Superfamily member 18, TNFRSF18, Activation-Inducible TNFR Family Receptor, AITR, and CD357

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Product Data Gallery

4-20% SDS-PAGE Coomassie Staining

GITRL:GITR-biotin Binding

Gel Filtration Trace

GITR: GITRL inhibition curve using a TR-FRET assay (#79054). Representative data only; data may vary by lot.

Product Info

Storage and Usage

Citations

Species

Human

Host Species/Expression System

HEK293

Purity

≥90%

Formulation

8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol

MW

43 kDa

Amino Acids

26-161

Genbank #

NM_004195

UniProt #

Q9Y5U5

Tag(s)

C-terminal Fc fusion (Human IgG1)

Label

This protein is enzymatically biotinylated using Avi-Tag™ technology. Biotinylation confirmed to be ≥90%.

For more information on enzymatic biotinylation, please see our Tech Note.

References

1. Shimizu, J., et al., Nat. Immunol. 2002; 3: 135-142.

2. Ko, K., et al., J. Exp. Med. 2005; 202(7): 885-891.

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Datasheets/Protocols

71256_Lot150611.pdf

Datasheets provide example lot-specific information. Contact us to request information on currently available lots.

● General Protocols

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