GITR (CD357), Fc fusion (Human) HiP™

Catalog #: 71172
Size: 100 µg
$310
Species: Human
Host Species: HEK293
MW: 41.2 kDa
Genbank #: NM_004195
Tag(s): C-terminal Fc fusion (Human IgG1)
a.a: 26-161
Description:

Human secreted GITR, Fc fusion protein, also known as Glucocorticoid-induced TNFR-Related Protein, Tumor Necrosis Factor Receptor Superfamily member 18, TNFRSF18, Activation-Inducible TNFR Family Receptor, AITR, and CD357, GenBank Accession No. NM_004195, a.a. 26-161 expressed in a HEK293 cell expression system. MW = 41.2 kDa (monomer). This protein runs at a higher MW by SDS-PAGE due to glycosylation.

UniProt
Q9Y5U5
Synonym(s):
Glucocorticoid-induced TNFR-Related Protein, Tumor Necrosis Factor Receptor Superfamily member 18, TNFRSF18, Activation-Inducible TNFR Family Receptor, AITR, CD357
Endotoxin Level:
<1 EU/μg
Formulation:
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Format:
Aqueous buffer solution
Storage / Stability:
At least 6 months at –80°C.
Application(s):
Useful for studying protein binding and screening small molecules.
Reference(s):
1. Shimizu, J., et al., Nat. Immunol. 2002; 3: 135-142.
2. Ko, K., et al., J. Exp. Med. 2005; 202(7): 885-891.
Notes:
HiP™ indicates a high purity protein with ≥90% purity as measured by gel filtration.
Warning(s):
Avoid freeze/thaw cycles. Protein may be diluted to ≥ 100 μg/ml in PBS + glycerol and stored at -80°C.
Scientific Category:
Immunotherapy
Product Type:
Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.

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Product Datasheets

71172_Lot140520-D.pdf