Geldanamycin, FITC-labeled

Catalog #
50312
$165 *
Size: 30 µl
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Description

A novel geldanamycin fluorescent probe optimized for use with BPS's HSP90 Assay Kits. May also be used for detection of cell surface HSP90.

This product has been cited 5 times.

Product Info
Storage and Usage
Citations5
Purity
≥98%
Format
DMSO solution (2.5 µM)
Formulation
C55H63N5O13S
Concentration
2.5 µM
MW
1034.2 Da
Biological Activity
FITC-labeled geldanamycin has been shown to inhibit HSP90 protein with an IC50 of 60 nM and HSP90 with an IC50 of 84 nM as shown. Measured using the HSP90 Assay Kits.
CAS Registry #
30562-34-6 (Geldanamycin)
References
1. Kim, J., et al., Biomol. Screening 2004; 9(5): 375-381.
2. Howes, R., et al., Anal. Biochem. 2006; 350:202-213.