Fluorogenic DPP substrate2

Catalog #: 80332
Size: 100 µl
MW: 621.7 Da
CAS Registry #: 88937-61-5
Formula: C30H39N9O6
The fluorogenic DPP substrate 2 is an Arg-Arg-AMC dipeptide. It can be used as a substrate for activity assays of DPP3. λex 353-380 nm, λem=440-460 nm
Z-Arg-Arg-AMC, Z-R-R-AMC, Benzyloxycarbonyl- L-arginyl- L-arginine- 4-methylcoumaryl-7-amide
Supplied As:
0.5 mM solution in DMSO (100 µl)
DMSO solution
Storage / Stability:

Stable at least 6 months from date of receipt, when stored as directed

Useful for the study of DPP3 activity, and for screening small molecule inhibitors of DPP3 for drug discovery and HTS applications. Can also be used as a substrate for cathepsin B.

1. Dhanda S. et al., Protein Expr Purif. 2007, 52(2):297-305.
2. Agic D. et al., Bioorg Chem. 2007, 35(2):153-69.

Application Reference(s):
1. Design, synthesis and anti-diabetic activity of triazolotriazine derivatives as dipeptidyl peptidase-4 (DPP-4) inhibitors (2017)

Protect from direct exposure to light. Avoid freeze/thaw cycles.
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