FAP, His-Tag (Mouse) Recombinant
Catalog #
100226
$470
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Description
Recombinant mouse FAP (fibroblast activation protein), encompassing amino acids 26-762(end). This construct contains C-terminal His-tag (6xHis). The recombinant protein was affinity purified.
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Synonyms
Prolyl endopeptidase FAP, 170 kDa melanoma membrane-bound gelatinase, Dipeptidyl peptidase FAP, Fibroblast activation protein alpha (FAPalpha), Gelatine degradation protease FAP, Integral membrane serine protease, SIMP, Seprase
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Product Data Gallery
4-20% SDS-Page Coomassie Staining
Product Info
Storage and Usage
Citations
Species
Mouse
Construct
FAP (26-762(end)-His)
Host Species/Expression System
HEK293
Purity
≥90%
Format
Aqueous buffer solution
Formulation
8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol
MW
88 kDa + glycans
Amino Acids
26-762(end)
Glycosylation
This protein runs at a higher MW by SDS-PAGE due to glycosylation.
Genbank #
NM_007986
UniProt #
Q12884
Background
FAP expression is seen on activated stromal fibroblasts in >90% of
all human carcinomas, suggesting a role in the development, growth and metastasis of
carcinomas. It is also involved in the control of wound healing and tissue repair.
References
1. Edosada,C.Y. et al., J. Biol. Chem. 281 (11),
7437-7444 (2006).
2. Edosada,C.Y. et al., FEBS Lett. 580 (6), 1581-1586 (2006).
2. Edosada,C.Y. et al., FEBS Lett. 580 (6), 1581-1586 (2006).
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