Kaempferol

Catalog #
27757
$135 *
Size: 50 mg
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Description

Naturally occurring flavonoid found in Gingko biloba and red wines that activates the mitochondrial Ca2+ uniporter (EC50 = 7 μM). Induces caspase-9-mediated apoptosis in a variety of cancer cell lines via downregulation of polo-like kinase 1 (PLK1) expression. Exhibits antioxidant activity and attenuates osteoclastic bone reabsorption in vitro.

Synonyms
Robigenin; Kempferol; Kaempherol; Populnetin; Rhamnolutein; Trifolitin; Pelargidenolon; Rhamnolutin; Swartziol; 3,5,7-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one
Product Info
Storage and Usage
Citations
Purity

≥99%

Format
yellow coloured powder
Target(s)
HDAC
Formula
C15H10O6
MW
286.2 Da
Solubility

insoluble in H2O; insoluble in EtOH; ≥12.25 mg/mL in DMSO

CAS Registry #
520-18-3
References
1. Kim SH, Choi KC. Toxicol Res. 2013 Dec 31;29(4):229-34.
2. Chen AY, Chen YC. Food Chem. 2013 Jun 15;138(4):2099-107.