DDR2, GST-tag Recombinant

Catalog #
40185
$410 *
Size: 10 µg
Qty
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Description

Recombinant human DDR2 (467-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST-tag. The gene accession number is NM_006182.

Synonyms
TKT, NTRKR3, TYRO10, DDR-2
Product Info
Storage and Usage
Citations
Species
Human
Host Species/Expression System
Sf9 insect cells
Purity
≥90%
Format
Aqueous buffer solution
Formulation
50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
MW
70 kDa
Amino Acids
467–end
Specific Activity
25 pmol/min/µg
Genbank #
NM_006182
UniProt #
Q16832
Tag(s)
N-terminal GST-tag
Background
DDR2 is a member of a novel subclass of RTKs containing a distinct extracellular region encompassing a factor VIII-like domain (1) and is thought to be involved in the regulation of cell growth, differentiation, and metabolism. DDR2 plays a role in the regulation of collagen turnover mediated by smooth muscle cells in obstructive diseases of blood vessels and the lung (2).
References
1. Karn, T. et al. Oncogene 8: 3433-3440, 1993.
2. Ferri, N. et al. Am J Pathol. 2004 May,164(5):1575-85.