Curcumin

Catalog #

27104

$150 *

Size: 100 mg

Qty

Bulk/Custom

Add to Favorites

*US Pricing only. For international pricing, please contact your local distributor.

●

Purchase

●

Description

Curcumin, also known as diferuloylmethane, natural yellow 3, or C.I. 75300, is the principal curcuminoid of the popular Indian spice turmeric, which is a small molecule, selective HAT inhibitor. It has shown to promote degradation of p300 and inhibits the acetyltransferases activity of purified p300 using either histone H3 or p53 as a substrate.

This product has been cited 2 times.

●

Synonyms

Curcumin, diferuloylmethane, natural yellow 3, C.I. 75300

●

Product Data Gallery

Product Info

Storage and Usage

Citations2

Purity

≥94% by HPLC

Format

Yellow powder.

Formula

C₂₁H₂₀O₆

368.4 Da

Solubility

Soluble in acetone, ethanol and DMSO.

Biological Activity

Acetylation of histones H3 and H4 by p300/CBP was strongly inhibited by curcumin with an IC50 25 µM.

CAS Registry #

458-37-7

References

1. Marcu, MG. et al., Med. Chem. 2006 Mar; 2(2): 169-174.
2. Kundu, TK. et al., Journal of Biological Chemistry (2004); 279(49):51163-51171.

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Curcumin

PRODUCTS

SERVICES

RESOURCES

COMPANY