Cell Lines

Cell lines have become an extremely useful tool for the study of protein interactions, gene activation, and other biological processes in a more natural biological system than cell-free assays. BPS has developed and selected for numerous stable cell lines that are applicable for a wide range of research applications. Additionally, BPS has a Cell Line Rental Program for select cell lines.

Luciferase Reporter Cell Lines
BPS’s cell signaling cell lines utilize the firefly luciferase reporter system. Our luciferase reporter constructs contain the firefly luciferase gene downstream of a response element that is specific for the particular cell signaling pathway being studied. Upon transcription factor binding to the response element, luciferase protein is transcribed. After addition of luciferin, luciferase converts luciferin to oxyluciferin in a reaction that gives off light. This bioluminescent reaction is readily detected and the amount of light given off is proportional to the amount of luciferase that has been transcribed and translated in the cells. Our portfolio is continually growing and currently includes a number of disease-relevant signaling pathways such as Notch, Wnt, Hippo, ARE, Gli, and many more.

BPS Bioscience provides signaling pathway screening services to investigate cell signaling pathways and signal transduction. In addition to luciferase reporter cell lines, BPS also offers cell lines for studying ion channels, ion transporters, phosphodiesterases, and G protein-coupled receptors (GPCRs). All of our cell lines have been extensively validated and are provided with detailed protocols that include instructions for general cell culture and maintenance, as well as example experimental setups. Each cell line is tested for viability and biological activity before shipping to ensure valid, reproducible results and to minimize the need for end-user optimization and troubleshooting.

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Catalog#SizeProduct NamePrice
60613 500 reactions ISRE Reporter Kit (JAK/STAT Signaling Pathway)
$565
60510 2 vials ISRE Reporter – HEK293 Recombinant Cell Line (JAK pathway)
$1,495
71278 2 vials LAG3 / NFAT Reporter - Jurkat Recombinant Cell Line
$8,800
79262 2 Vials LIGHT-CHO Recombinant Cell Line
$6,000
60509 500 reactions Mouse Notch1 Pathway Reporter Kit (Notch Signaling Pathway)
$590
60520 2 vials Myc Reporter (Luc) – HCT116 Recombinant Cell Line (Myc Signaling Pathway)
$1,335
60519 500 reactions Myc Reporter Kit (Myc Signaling Pathway)
$565
60507 2 vials NaV1.7–HEK293 Recombinant Cell Line
$8,800
60521 2 vials Nav1.8/β2 - HEK293 Recombinant Cell Line
$8,800
79578 500 µl x 2 Negative Control Lentivirus (Firefly Luciferase)
$795
60557 2 vials NET – CHOK1 Recombinant Cell Line
$8,650
79645 2 vials NF- κB Reporter (Luc) – THP-1 Cell Line
$1,425
60622 2 vials NF-κB Reporter (Luc) - CHO-K1 Recombinant Cell Line
$875
60623 2 vials NF-κB Reporter (Luc) - HCT116 Recombinant Cell Line
$875
60651 2 vials NF-κB Luciferase Reporter (Luc) - Jurkat Recombinant Cell Line
$1,500
79564 500 µl x 2 NF-κB Luciferase Reporter Lentivirus
$795
60625 2 vials NF-κB Reporter (Luc) - A549 Recombinant Stable Cell Line
$1,425
60650 2 vials NF-κB reporter (Luc) - HEK293 Recombinant Cell line
$935
79469 2 vials NF-κB reporter (Luc) – NIH/3T3 Cell line
$1,425
60614 500 reactions NF-κB Reporter Kit (NF-κB Signaling Pathway)
$590
60621 2 vials NFAT Reporter (Luc) – Jurkat Recombinant Cell Line
$1,500
79298 2 Vials NFAT Reporter – Hek293 Cell Line (PKC/ Ca2+ Pathway)
$1,425
79059 30 million cells Normal Human Peripheral Blood Mononuclear Cells, Frozen
$190
60652 2 vials Notch Signaling Pathway Notch1/CSL Reporter - HEK293 Recombinant Cell Line
$1,500
79504 500 reactions Notch1 NICD Pathway Reporter Kit (Mouse)
$590

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