Cell Lines

Cell lines have become an extremely useful tool for the study of protein interactions, gene activation, and other biological processes in a more natural biological system than cell-free assays. BPS has developed and selected for numerous stable cell lines that are applicable for a wide range of research applications. Additionally, BPS has a Cell Line Rental Program for select cell lines.

Luciferase Reporter Cell Lines
BPS’s cell signaling cell lines utilize the firefly luciferase reporter system. Our luciferase reporter constructs contain the firefly luciferase gene downstream of a response element that is specific for the particular cell signaling pathway being studied. Upon transcription factor binding to the response element, luciferase protein is transcribed. After addition of luciferin, luciferase converts luciferin to oxyluciferin in a reaction that gives off light. This bioluminescent reaction is readily detected and the amount of light given off is proportional to the amount of luciferase that has been transcribed and translated in the cells. Our portfolio is continually growing and currently includes a number of disease-relevant signaling pathways such as Notch, Wnt, Hippo, ARE, Gli, and many more.

BPS Bioscience provides signaling pathway screening services to investigate cell signaling pathways and signal transduction. In addition to luciferase reporter cell lines, BPS also offers cell lines for studying ion channels, ion transporters, phosphodiesterases, and G protein-coupled receptors (GPCRs). All of our cell lines have been extensively validated and are provided with detailed protocols that include instructions for general cell culture and maintenance, as well as example experimental setups. Each cell line is tested for viability and biological activity before shipping to ensure valid, reproducible results and to minimize the need for end-user optimization and troubleshooting.

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Catalog#SizeProduct NamePrice
60544 2 Vials PAI-1 Reporter (Luc) – Mv1 Lu Cell Line
$2,595
60680 2 vials PD-1 - HEK293 Recombinant Cell Line
$3,850
60535 2 vials PD-1 / NFAT Reporter - Jurkat Recombinant Cell Line
$8,000
60800 100 reactions PD-1:PD-L1/PD-L2 Cell-Based Inhibitor Screening Assay Kit
$1,040
60543 2 vials PD-L1 - CHO Recombinant Cell Line
$3,750
60536 2 vials PD-L1 / TCR Activator - CHO Recombinant Cell Line
$8,000
60410 2 vials PDE10A-HEK293 Recombinant Cell line
$7,500
60402 2 vials PDE1B-HEK293 Recombinant Cell line
$7,500
60407 2 vials PDE7A-HEK293 Recombinant Cell Line
$7,500
60413 2 vials PDE7A/CRE Reporter - HEK293 Recombinant Cell Line
$7,500
60412 2 vials PDE7B-HEK293 Recombinant Cell Line
$7,500
60503 2 vials RARα Reporter - HEK293 Recombinant Cell Line
$1,375
60603 2 vials RARβ Reporter - HEK293 Recombinant Cell Line
$1,295
60604 2 vials RARγ Reporter - HEK293 Reporter Cell Line
$1,295
60408 2 vials rPDE7A-HEK293 Recombinant Cell Line
$7,500
60689 2 vials SIRP-α / HEK293 Recombinant Cell Line
$3,675
90333 2 vials SLC5A5 – HEK293 Recombinant Cell line
$7,875
60406 2 vials SRE Reporter - HEK293 Recombinant Cell Line (ERK Pathway)
$1,295
60501 2 vials TCF/LEF reporter-HEK293 Recombinant cell line (Wnt Signaling Pathway, Lithium Chloride Dependent)
$1,375
60556 2 vials TCR Activator - Raji Cell Line
$7,875
60610 500 reactions TCR Activator / PD-L1 Mammalian Expression Kit
$575
60620 500 reactions TCR Activator / PD-L2 Mammalian Expression Kit
$550
72033 100 reactions TDO Cell-Based Assay Kit
$550
62002-1 100 reactions TDO Cellular Activity QuickDetect™ Supplements
$205
62002-2 1000 reactions TDO Cellular Activity QuickDetect™ Supplements
$1,040

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