Cell Lines

Cell lines have become an extremely useful tool for the study of protein interactions, gene activation, and other biological processes in a more natural biological system than cell-free assays. BPS has developed and selected for numerous stable cell lines that are applicable for a wide range of research applications. Additionally, BPS has a Cell Line Rental Program for select cell lines.

Luciferase Reporter Cell Lines
BPS’s cell signaling cell lines utilize the firefly luciferase reporter system. Our luciferase reporter constructs contain the firefly luciferase gene downstream of a response element that is specific for the particular cell signaling pathway being studied. Upon transcription factor binding to the response element, luciferase protein is transcribed. After addition of luciferin, luciferase converts luciferin to oxyluciferin in a reaction that gives off light. This bioluminescent reaction is readily detected and the amount of light given off is proportional to the amount of luciferase that has been transcribed and translated in the cells. Our portfolio is continually growing and currently includes a number of disease-relevant signaling pathways such as Notch, Wnt, Hippo, ARE, Gli, and many more.

BPS Bioscience provides signaling pathway screening services to investigate cell signaling pathways and signal transduction. In addition to luciferase reporter cell lines, BPS also offers cell lines for studying ion channels, ion transporters, phosphodiesterases, and G protein-coupled receptors (GPCRs). All of our cell lines have been extensively validated and are provided with detailed protocols that include instructions for general cell culture and maintenance, as well as example experimental setups. Each cell line is tested for viability and biological activity before shipping to ensure valid, reproducible results and to minimize the need for end-user optimization and troubleshooting.

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Catalog#SizeProduct NamePrice
60522 500 reactions GAL4 Reporter Kit (Glucocorticoid Receptor Pathway)
$565
79041 2 vials GAS Reporter (Luc) – HeLa Cell Line (IFNγ/JAK/STAT1 Pathway)
$1,425
60546 2 vials GITR / NF-κB Luciferase Reporter (Luc) - Jurkat Cell Line
$8,800
79092 2 vials GITR - HEK293 Recombinant Cell Line
$4,025
60547 2 vials GITRL CHO-K1 Recombinant Cell Line
$4,125
60409 2 vials Gli Reporter – NIH3T3 Recombinant Cell line (Hedgehog Pathway)
$1,500
60655 2 vials GR-GAL4 Reporter (Luc)-HEK293 Recombinant Cell Line (Glucocorticoid Receptor Pathway)
$1,500
79647 96 reactions Growth Arrested PD-L1 - CHO Recombinant Cell Line
$590
79528 500 ml Growth Medium 1A
$600
79531 500 ml Growth Medium 1B
$600
79532 500 ml Growth Medium 1C
$600
79536 500 ml Growth Medium 1D
$600
79540 500 ml Growth Medium 1F
$600
79544 500 ml Growth Medium 1G
$600
79533 500 ml Growth Medium 1K
$600
60190 500 ml Growth Medium 2A
$600
79530 500 ml Growth Medium 2B
$600
79592 500 ml Growth Medium 2C
$600
79638 500 ml Growth Medium 2E
$600
79669 500 ml Growth Medium 2F
$600
60188 500 ml Growth Medium 3A
$600
79529 500 ml Growth Medium 3B
$600
79537 500 ml Growth Medium 3C
$600
79539 500 ml Growth Medium 3D
$600
79535 500 ml Growth Medium 4A
$600

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