Cell Lines and Primary Cells

Cell lines are extremely useful tools for the study of protein interactions, gene activation, cell signaling, viral infection, cell-to-cell communication, and other biological processes in the context of an intact cell system rather than cell-free biochemical assays. BPS Bioscience has developed over 250 stable cell lines applicable across a wide range of research areas including immunotherapy, CAR-T cell therapy, cell signaling, metabolism, neuroscience, and much more. We now also feature iPSC-derived cells for drug discovery.

Unlock new discoveries with our Cell Line Rental Program

Rent for 3 months at 50% of the cost. Some restrictions apply.

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Get More with our Cell Line Subscription

The subscription allows for the purchase of a cell line product with additional vials at low cost, plus the optional benefit of cell banking and shipment upon request.

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Luciferase Reporter Cell Lines

Many of our cell lines utilize the firefly luciferase reporter system, in which the firefly luciferase gene is downstream of a response element specific to a particular cell signaling pathway. Upon transcription factor binding to the response element, luciferase RNA is transcribed and translated into a functional luciferase protein. After addition of luciferin, luciferase converts luciferin to oxyluciferin in a reaction that gives off light. This bioluminescent reaction is readily detected, and the amount of light is proportional to the expression of luciferase. Learn more about our luciferase reporter cell lines in this video.

All our cell lines have been extensively validated, confirming biological activity when appropriate, and are provided with detailed protocols that include instructions for general cell culture and maintenance, as well as example experimental setups. Each cell line is tested for viability and mycoplasma before shipping to ensure valid, reproducible results and to minimize the need for end-user optimization and troubleshooting.

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Custom Cell Line Development

With our cell line development services, we can engineer cell lines with a knocked-out protein, stably expressing proteins at high, homogeneous levels, or bearing reporter constructs. Each project is customized for the desired deliverables through working directly with our team of highly trained scientists using a milestone-measured process.

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Signaling Pathway Screening Services

BPS Bioscience provides signaling pathway screening services to investigate cell signaling pathways and signal transduction.

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Cell Lines and Cell Pools License Disclosure

Purchase of these cells grants you with a 10-year license to use the cells and their progeny in your immediate laboratory, for research use only. Commercial use of the cells is not permitted under this license. This license does not permit you to share, transfer, distribute, sell, sublicense, or otherwise make the cells available for use to other researchers, laboratories, departments, research institutions, hospitals, universities, CROs, or biotech companies. The license does not permit use of the cells in humans or for therapeutic or drug use. The license does not permit modification of the cells in any way. Inappropriate use or distribution of the cells will result in revocation of the license and result in an immediate cease of sales and distribution of BPS Bioscience products to your laboratory. BPS Bioscience does not warrant the suitability of the cells for any particular use, and does not accept any liability in connection with the handling or use of the cells. Modifications of the cells, transfer to another facility, or commercial use of the cells may require a separate license and additional fees; contact [email protected] for details. Publications using the cells should reference BPS Bioscience, Inc., San Diego.

Limited Use License Agreement Form