Cell Lines

Cell lines have become an extremely useful tool for the study of protein interactions, gene activation, and other biological processes in a more natural biological system than cell-free assays. BPS has developed and selected for numerous stable cell lines that are applicable for a wide range of research applications. Additionally, BPS has a Cell Line Rental Program for select cell lines.

Luciferase Reporter Cell Lines
BPS’s cell signaling cell lines utilize the firefly luciferase reporter system. Our luciferase reporter constructs contain the firefly luciferase gene downstream of a response element that is specific for the particular cell signaling pathway being studied. Upon transcription factor binding to the response element, luciferase protein is transcribed. After addition of luciferin, luciferase converts luciferin to oxyluciferin in a reaction that gives off light. This bioluminescent reaction is readily detected and the amount of light given off is proportional to the amount of luciferase that has been transcribed and translated in the cells. Our portfolio is continually growing and currently includes a number of disease-relevant signaling pathways such as Notch, Wnt, Hippo, ARE, Gli, and many more.

BPS Bioscience provides signaling pathway screening services to investigate cell signaling pathways and signal transduction. In addition to luciferase reporter cell lines, BPS also offers cell lines for studying ion channels, ion transporters, phosphodiesterases, and G protein-coupled receptors (GPCRs). All of our cell lines have been extensively validated and are provided with detailed protocols that include instructions for general cell culture and maintenance, as well as example experimental setups. Each cell line is tested for viability and biological activity before shipping to ensure valid, reproducible results and to minimize the need for end-user optimization and troubleshooting.

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Catalog#SizeProduct NamePrice
79092 2 vials GITR - HEK293 Recombinant Cell Line
$3,675
60547 2 vials GITRL CHO-K1 Recombinant Cell Line
$7,500
60409 2 vials Gli Reporter – NIH3T3 Recombinant Cell line (Hedgehog Pathway)
$1,375
60655 2 vials GR-GAL4 Reporter (Luc)-HEK293 Recombinant Cell Line (Glucocorticoid Receptor Pathway)
$1,375
71227 2 vials HEK293 - T-REx Recombinant Cell Line
$1,025
60619 2 vials hERG (Kv11.1) - HEK293 Recombinant Cell line
$1,375
60618 2 vials Hippo Pathway TEAD Reporter - MCF7 Recombinant Cell Line
$1,375
79297 2 vials HVEM - CHO Recombinant Cell Line
$5,500
79313 2 vials HVEM - HEK293 Recombinant Cell Line
$3,675
79310 2 vials HVEM/NF-κB Reporter Jurkat Recombinant Cell Line
$8,000
72031 100 reactions IDO1 Cell-Based Assay Kit
$550
62000-1 100 reactions IDO1 Cellular Activity QuickDetect™ Supplements
$205
62000-2 1000 reactions IDO1 Cellular Activity QuickDetect™ Supplements
$1,040
60532 2 vials IDO1-HEK293 Recombinant Cell line (Human)
$8,000
60533 2 vials IDO2 - HEK293 Recombinant Cell Line (Human)
$8,000
62001-1 100 reactions IDO2 Cellular Activity QuickDetect™ Supplements
$205
62001-2 1000 reactions IDO2 Cellular Activity QuickDetect™ Supplements
$1,040
90330 2 vials IKCA1 (KCNN4) - HEK293 Recombinant Cell Line
$7,500
60481 2 vials IL-2-Luciferase Reporter (Luc) - Jurkat Cell Line
$5,250
60510 2 vials ISRE Reporter – HEK293 Recombinant Cell Line (JAK pathway)
$1,295
71278 2 vials LAG3 / NFAT Reporter - Jurkat Recombinant Cell Line
$8,000
79262 2 Vials LIGHT-CHO Recombinant Cell Line
$5,500
60520 2 vials Myc Reporter (Luc) – HCT116 Recombinant Cell Line (Myc Signaling Pathway)
$1,295
60507 2 vials NaV1.7–HEK293 Recombinant Cell Line
$8,000
60521 2 vials Nav1.8/β2 - HEK293 Recombinant Cell Line
$8,000

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