CDK4(EE,T172A)/Cyclin D1, His-tag Recombinant

Catalog #
40094
$355 *
Size: 20 µg
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Description

Complex of recombinant, full length human CDK4 (GenBank accession number NM_000075) with C-terminal His-tag and modifications (a.a. 43G-47G were replaced with EE, and T172A), and human Cyclin D1 (GenBank accession number NM_053056), a.a. 16-271, were co-expressed in a baculovirus-infected Sf9 cells expression system. CDK4 MW=34 kDa, Cyclin D1 MW=29 kDa.

This product has been cited 1 time.

Synonyms
Cyclin-Dependent Kinase 4, Cell Division Kinase 4, CDK4, Cyclin D1, CCD1, Bcl1, PRAD1, CCND1, CDK-4
Product Info
Storage and Usage
Citations1
Species
Human
Host Species/Expression System
Sf9 insect cells
Purity

≥90%

Format
Aqueous buffer solution
Formulation
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.05% Tween-20, 20% glycerol, and 3 mM DTT.
MW
63 kDa (complex)
Amino Acids
full length
Genbank #
NM_000075(CDK4), NM_053056(cyclin D1)
UniProt #
P11802 (CDK4), P24385 (cyclin D1)
Tag(s)
C-terminal His-tag (CDK4), no tag on Cyclin D1
References

1. Amendola D. et al., Cell Prolif. 2009. Feb; 42(1):94-109.
2. Yang L. et al., Biochem Cell Biol. 2009. Dec; 87(6):933-42.