CD40, Fc fusion (Human)

Catalog #: 71174
Size: 100 µg
$310
Species: Human
Host Species: HEK293
MW: 45.9 kDa
Genbank #: NM_001250
Tag(s): C-terminal Fc fusion (Human IgG1)
a.a: 21-193
Description:

Human secreted CD40, Fc fusion protein, also known as Tumor Necrosis Factor Receptor Superfamily Member 5, TNFRSF5, and Bp50, GenBank Accession No. NM_001250, a.a. 21-193 expressed in a HEK293 cell expression system. MW = 45.9 kDa (monomer). This protein runs at a higher MW by SDS-PAGE due to glycosylation.

UniProt
P25942
Synonym(s):
Tumor Necrosis Factor Receptor Superfamily Member 5, TNFRSF5, Bp50
Endotoxin Level:
<1 EU/μg
Formulation:
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Format:
Aqueous buffer solution.
Storage / Stability:
At least 6 months at –80°C
Application(s):
Useful for studying protein binding and screening small molecules.
Reference(s):

1. Wilcox, R.A., et al., J. Clin. Invest. 2002; 109(5): 651-659.

2. Foell, J. et al., J. Clin. Invest. 2003; 111(10): 1505-1518.

Notes:
The aggregation state of this product has been confirmed to be <10%.
Warning(s):
Avoid freeze/thaw cycles. Protein may be diluted to ≥ 100 μg/ml in PBS + glycerol and stored at -80°C.
Scientific Category:
Immunotherapy
Product Type:
Recombinant Protein
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Product Datasheets

71174_Lot140528-D.pdf