Viral Tools Frequently Asked Questions
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Lentiviruses
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How should I store the viral particles (lentivirus, AAV or VSV) that I just rec...
Frequently Asked Questions
BPS Bioscience is here to answer your questions and provide project guidance. On the following pages, we outline some of the most frequently asked questions separated by product type. If your question is not answered through these resources, please contact us today and we are happy to assist.
Proteins
Cell Lines
Assay Kits ...
VSV Tools
VSV (Vesicular stomatitis virus) is an enveloped, negative-stranded RNA virus with a simple structure. Its ability to infect a wide range of mammalian cell types has made VSV a valuable tool to study virus entry, replication, and assembly. The glycoprotein of VSV (termed VSV-G), which binds to the LDL-receptor (low-density lipoprotein receptor), is responsible for the attachment and entry of VSV into a susceptible host cell.
The VSV-G glycoprotein can be deleted from the VSV (V...
Custom AAV Services
Adeno-Associated Viruses (AAV) are useful for gene therapy due to their gene transfer efficiency and safety. Inside the cell, AAVs are episomal and result in the sustained expression of a gene of interest for up to 6 months in non-dividing cells. Our off-the-shelf AAVs can be used in a Biosafety Level 1 (BSL-1) facility.
BPS Bioscience is developing a portfolio of AAV products to support your research needs. Our custom s...
The Power of Lentiviruses in Cell Engineering
Introduction
The ability to manipulate nucleic acids has been a key discovery that has driven research, and ultimately clinical applications, forward. It opened the door to study the impact of mutations in cellular models, dissect pathways, generate recombinant proteins and monoclonal antibodies, and is the basis of gene and cell therapy, continuing to lead to new discoveries and cure patients every day. The methods used to ...
SARS-CoV-2 Antibody Detection
SARS-CoV-2 has spread across the globe effectively at a rapid pace causing a worldwide pandemic. Infection with this highly contagious respiratory virus can be asymptomatic or present as COVID-19, a disease with varying degrees of severity. Clinical symptoms may include fever, dry cough, anosmia, gastrointestinal symptoms, hypercoagulability, hyperimmune response (cytokine storm), and acute respiratory distress syndrome (ARDS) with disease progression (1). Patie...
Polybrene-based Viral Transduction Protocol
Polybrene is a cationic polymer that acts by neutralizing the charge repulsion between the virus and the cell surface (both negatively charged), thus increasing the transduction efficiency.
Polybrene is a cationic polymer that acts by neutralizing the charge repulsion between the virus and the cell surface (both negatively charged), thus increasing the transduction efficiency. ...
Citations
This page contains a list of scientific journal articles that have cited BPS products and services since 2013. We would like to congratulate all our loyal customers on their contributions to the scientific community. Our customers are truly amazing and dedicated scientists and this is evidenced by the outstanding research they are doing.
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10X HAT Assay Buffer (50095...
