Caspase7, His-tag Recombinant

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Catalog #
70000
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Description

Human Caspase-7 (full length) (GenBank Accession No. NM_001227) with C-terminal His-tag, MW= 35.1 kDa, expressed in an E. coli expression system. Active caspase 7 is a heterotetramer consisting of two copies each of ~20 kDa and ~11 kDa subunits.

Synonyms
Caspase-7, CASP7, Caspase 7, Mch3, ICE-LAP3, Caspase
Product Info
Storage and Usage
Citations
Species
Human
Host Species/Expression System
E. coli
Purity

≥90%

Format
Aqueous buffer solution
Formulation
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 155 mM imidazole, 20% glycerol and 3 mM DTT.
MW
35.1 kDa
Amino Acids
full length
Specific Activity
≥ 5337 pmol/min/µg
Genbank #
NM_001227
UniProt #
P55210
Tag(s)
C-terminal His-tag
Background
Caspase-7 is a member of the caspase (cysteine aspartate protease) family of proteins, and has been shown to be an executioner protein of apoptosis.
References
Wang DH., et al., PLoS one,7(6):e39920. doi:10.1371/journal.0039920. (2012).