Bap1, His-tag Recombinant
Catalog #
81083
$315
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Description
BAP1 is a deubiquitinase that plays a key role in chromatin by mediating deubiquitination of histone H2A and HCFC1. It acts as a regulator of cell growth.
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Synonyms
BRCA1-associated protein 1, Cerebral protein 6, DKFZp686N04275, FLJ35406, FLJ37180, HUCEP-13, hucep-6, KIAA0272, Ubiquitin carboxyl-terminal hydrolase BAP1
Product Info
Storage and Usage
Citations
Species
Human
Host Species/Expression System
E. coli
Format
Aqueous buffer solution
MW
82 kDa
UniProt #
Q92560
Background
BAP1 is the first large, nuclear-localized UCH to be identified. It is a protein of 90 kDa that binds to the BRCA RING finger and enhances BRCA1-mediated cell growth suppression.
References
David E. Jensen and Frank J. Rauscher III. BAP1, a Candidate Tumor Suppressor Protein that Interacts with BRCA1. Ann N Y Acad Sci. 1999. 886: p191-4.
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