BACE1, His-Tag (Human) Recombinant
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Catalog #
71657
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Description
Recombinant human BACE1 (beta-site amyloid precursor protein cleaving enzyme 1), encompassing amino acids 22-460. This construct contains a C-terminal His-tag (10xHis). The recombinant protein was affinity purified.
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Synonyms
Beta-secretase 1, Aspartyl protease 2, ASP2, ASP 2, beta-site amyloid precursor protein cleaving enzyme 1, Beta-site APP cleaving enzyme 1, Memapsin-2, Membrane-associated aspartic protease 2, BACE, KIAA1149
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Product Data Gallery
4-20% SDS-PAGE Coomassie Staining
BACE1 inhibition curve using a fluorogenic assay (#71656). Representative data only; data may vary by lot.
Product Info
Storage and Usage
Citations
Species
Human
Construct
BACE1 (22-460-His)
Host Species/Expression System
HEK293
Purity
≥90%
Format
Aqueous buffer solution
Formulation
8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, 20% glycerol
MW
50 kDa + glycans
Amino Acids
22-460
Glycosylation
This protein runs at a higher MW by SDS-PAGE due to glycosylation.
Genbank #
NM_012104
UniProt #
P56817
References
1. Luo, Y., et al., Neuroscience. 2001 4; 231-232.
2. Cai, H., et al., Neuroscience. 2001 4; 233-234.
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