B7-1 (CD80), Fc fusion (Human) HiP™ Recombinant

Catalog #
71125
$320 *
Size: 100 µg
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Description

Human secreted B7-1-Fc fusion protein, also known as CD80. GenBank Accession No. NM_005191, a.a. 35-242 expressed in a HEK293 cell expression system. MW = 50.5 kDa (monomer). This protein runs at a higher M.W. by SDS-PAGE due to glycosylation.

Synonyms
CTLA-4 Counter-Receptor B7.1
Product Info
Storage and Usage
Citations
Species
Human
Host Species/Expression System
HEK293
Purity

≥90%

Format
Aqueous buffer solution
MW
50.5 kDa
Amino Acids
35-242
Genbank #
NM_005191
UniProt #
P33681
Tag(s)
C-terminal Fc fusion (Human IgG1)
References

1. Byrum, J.N., Van Komen, J.S., Rodgers, W., J. Immunol. 2013 Sep 15;191(6):3073-3081.
2. Legat, A., et al., Front Immunol. 2013 Dec 19;4:455.

Application Reference(s):
1. Utilizing AlphaLISA Technology to Screen for Inhibitors of the CTLA-4 Immune Checkpoint (2017)