Axitinib
Catalog #
27064
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Description
Axitinib (AG-013736) is an oral, potent, and selective inhibitor of vascular endothelial growth factor receptors 1 (VEGFR-1), 2 (VEGFR-2), and 3 (VEGFR-3), platelet derived growth factor receptor (PDGFR), and cKIT (CD117).
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Synonyms
AG-013736
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Product Data Gallery
Product Info
Storage and Usage
Citations
Purity
≥99%
Format
White to off-white solid
Formula
C22H18N4OS
MW
386.5 Da
Solubility
Soluble in DMSO at 33 mg/ml; soluble in ethanol at 1.7 mg/ml with warming; very poorly soluble in water; maximum solubility in plain water is estimated to be about 10-50 µM.
CAS Registry #
319460-85-0
References
Mancuso, M.R., et al. J. Clin. Invest. 116: 2610-2621 (2006).