Anti-TIGIT Inhibitor Antibody

Catalog #: 71218
Size: 100 µg
$475
Host Species: HEK293
MW: 150 kDa
Tag(s): none
Clonality: Monoclonal
Isotype: IgG1
Description:
Recombinant human inhibitor antibody recognizing the TIGIT binding region on immune cells.
Assay Conditions:
Antibody was added to TIGIT: CD155 or TIGIT: CD112 homogenous assays at various concentrations. Assay was performed according to the protocol in BPS Cat #72029 or #72023, respectively.
Formulation:
8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol
Purification:
Protein A affinity chromatography from HEK293 supernatants.
Storage / Stability:
Stable for at least 12 months at -80°C. Avoid freeze/thaw cycles. Store diluted antibody with carrier protein (BSA 0.1 – 0.5%) at 4°C, stable for 2 weeks.
Application(s):
Useful for the inhibition of TIGIT: CD155 and TIGIT: CD112 interactions in biochemical assays. For neutralizing TIGIT in cellular assays, we recommend BPS Cat. #71340.
Reference(s):
1. Yu, X., et al., Nat. Immunol. 2009; 10(1): 48-57.

2. Stanietsky, N., et al., Proc. Natl. Acad. Sci. (USA). 2009; 106(42): 17858-17863.

Scientific Category:
Immunotherapy
Product Type:
Antibody
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Product Datasheets

71218.pdf