Anti–Setd1b polyclonal antibody

Catalog #
25314
$335 *
Size: 100 µl
Qty
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Description

Polyclonal antibody raised in rabbit against mouse Setd1b (Set domain containing 1B), using a 3 KLH–conjugated synthetic peptides containing sequences from the central part of the protein

This product has been cited 1 time.

Synonyms
SET1B, KMT2G
Product Info
Storage and Usage
Citations1
Clonality
polyclonal
Host Species/Expression System
Rabbit
Purification
Whole serum
Format
aqueous solution
Formulation
Whole antiserum from rabbit containing 0.05% azide
Concentration
100 µl
Immunogen
synthetic peptide
Background
SETD1B (UniProt/Swiss–Prot entry Q9UPS6) is a component of the SET1 histone methyltransferase (HMT) complex. This complex specifically methylates lysine 4 of histone H3, but only if the neighboring lysine 9 residue is not yet methylated. Methylation of H3K4 represents a specific tag for epigenetic transcriptional activation. SETD1B shows a non–overlapping localization with SETD1A, suggesting that both proteins play a specific role in the epigenetic control of chromatin structure and gene expression.