Anti–HDAC2 monoclonal antibody

Catalog #

25288

$415 *

Size: 50 µg

Qty

Bulk/Custom

Add to Favorites

*US Pricing only. For international pricing, please contact your local distributor.

●

Purchase

●

Description

Monoclonal antibody raised in mouse against human HDAC2 (Histone deacetylase 2), using a KLH–conjugated synthetic peptide containing a sequence from the C–terminal region of the protein.

This product has been cited 1 time.

●

Synonyms

HD2, RPD3, YAF1, HDAC-2

●

Product Data Gallery

Product Info

Storage and Usage

Citations1

Clonality

monoclonal

Host Species/Expression System

Mouse

Purification

Protein A purified

Format

Aqueous buffer solution

Formulation

PBS containing 0.05% azide and 0.05% ProClin 300

Concentration

50 µg/ 25 µl

Immunogen

synthetic peptide

Background

HDAC2 (UniProt/Swiss–Prot entry Q92769) belongs to the family of histone deacetylases which catalyse the deacetylation of lysine residues on the N–terminal part of the core histones (H2A, H2B, H3 and H4). Acetylation and deacetylation of these highly conserved lysine residues is important for the control of gene expression and HDAC2 activity is associated with gene repression. Histone deacetylation is established by the formation of large multiprotein complexes. Thereby, HDAC2 associates with many different proteins, including the mammalian zinc–finger transcription factor YY1. HDAC2 thus plays an important role in transcriptional regulation, cell cycle progression and developmental events.

Storage/Stability

Store at –80°C for up to 2 years. Centrifuge after first thaw to maximize product recovery. Aliquot to avoid repeated freeze/thaw cycles. Aliquots may be stored at –20°C for at least one month.

Assay Conditions

Western blot analysis using the monoclonal antibody directed against HDAC2
Whole cell extracts from HeLa cells (25 μg) were analysed by Western blot using the monoclonal antibody against HDAC2 (Cat. No. 25288) diluted 1:1,000 in TBS-Tween containing 5% skimmed milk. The position of the protein of interest is indicated on the right (expected size: 55 kDa); the marker (in kDa) is shown on the left.

Applications

WB (1:1000)

Shipping Temperature

-20°C or-80°C

Species Reactivity

Human

Notes

The optimal antibody concentration should be determined by the end–user.

Warnings

Avoid freeze/thaw cycles

Scientific Category

Antibodies

Regulatory Status

Research Use Only

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Anti–HDAC2 monoclonal antibody

PRODUCTS

SERVICES

RESOURCES

COMPANY