Anti–DNMT1 polyclonal antibody

Catalog #
25216
$335 *
Size: 100 µl
Qty
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Description

Polyclonal antibody raised in rabbit against mouse DNMT1 (DNA (cytosine–5)–methyltransferase 1), using a KLH–conjugated synthetic peptide containing an amino acid sequence from the C–terminal part of the protein

Synonyms
DNMT, MCMT, CXXC9, AIM, DNMT-1
Product Info
Storage and Usage
Citations
Clonality
polyclonal
Host Species/Expression System
Rabbit
Purification
Whole serum
Format
aqueous solution
Formulation
Whole antiserum from rabbit containing 0.05% azide
Concentration
100 µl
Immunogen
synthetic peptide
Background
DNMT1 (UniProt/Swiss–Prot entry P26358) preferentially methylates CpG residues in hemimethylated DNA and is responsible for maintaining methylation patterns established in development. Inactivation of DNMT1 causes global demethylation and embryonic lethality. DNA methylation is coordinated with methylation of histones. Transcriptional repression by DNMT1 is mediated by direct interaction with HDAC2