Aliskiren Hydrochloride

Catalog #

27300

$565 *

Size: 1 mg

Qty

Bulk/Custom

*US Pricing only. For international pricing, please contact your local distributor.

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Description

Aliskiren Hydrochloride is an orally active, synthetic nonpeptide Renin inhibitor that has been shown to work as an antihypertensive.

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Product Data Gallery

Product Info

Storage and Usage

Citations

Purity

≥95% by HPLC

Format

A crystalline solid.

Formula

C₃₀H₅₃N₃O₆•HCl

588.2 Da

Solubility

Soluble in methanol and chloroform.

Biological Activity

Aliskiren is one of the most potent renin inhibitors with an IC50 value of 0.6 nM.

CAS Registry #

173399-03-6

References

1. Wood, JM, et al., Biochem Biophys Res Commun. 2003 Sep 5;308(4):698-705.
2. Gradman, AH, et al., Circulation. 2005 Mar 1;111(8):1012-8.