AHA1, His-tag Recombinant

Catalog #
50291
$450 *
Size: 200 µg
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Description

Human recombinant full-length AHA1 with C-terminal His-tag (GenBank Accession No. NM_012111), expressed in E. coli. MW=38 kDa.

Synonyms
AHA1, ASHA1, Activator Of Heat Shock 90kDa Protein ATPase Homolog 1
Product Info
Storage and Usage
Citations
Species
Human
Host Species/Expression System
E. coli
Purity

≥90%

Format
Aqueous buffer solution
Formulation
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 3 mM DTT, 20% glycerol, and 200 mM imidazole
MW
38 kDa
Amino Acids
full length
Specific Activity
The addition of AHA1 increased ATPase activity of HSP90alpha from 0.18 to 0.94 pmol/min/µg.
Genbank #
NM_012111
UniProt #
O95433
Tag(s)
C-terminal His-tag
Background
Co-chaperone that stimulates HSP90 ATPase activity (By similarity). May affect a step in the endoplasmic reticulum to Golgi trafficking.
References
1. Wang, X. et al., Cell 127 (4), 803-815 (2006).
2. Lotz, G.P. et al., J. Biol. Chem. 278 (19), 17228-17235 (2003).