AHA1, His-tag Recombinant
Catalog #
50291
$450
*
●
●
Purchase
Description
Human recombinant full-length AHA1 with C-terminal His-tag (GenBank Accession No. NM_012111), expressed in E. coli. MW=38 kDa.
●
Synonyms
AHA1, ASHA1, Activator Of Heat Shock 90kDa Protein ATPase Homolog 1
●
Product Data Gallery
Product Info
Storage and Usage
Citations
Species
Human
Host Species/Expression System
E. coli
Purity
≥90%
Format
Aqueous buffer solution
Formulation
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 3 mM DTT, 20% glycerol, and 200 mM imidazole
MW
38 kDa
Amino Acids
full length
Specific Activity
The addition of AHA1 increased ATPase activity of HSP90alpha from 0.18 to 0.94 pmol/min/µg.
Genbank #
NM_012111
UniProt #
O95433
Background
Co-chaperone that stimulates HSP90 ATPase activity (By similarity). May affect a step in the endoplasmic reticulum to Golgi trafficking.
References
1. Wang, X. et al., Cell 127 (4), 803-815 (2006).
2. Lotz, G.P. et al., J. Biol. Chem. 278 (19), 17228-17235 (2003).
2. Lotz, G.P. et al., J. Biol. Chem. 278 (19), 17228-17235 (2003).