Aclacinomycin A

Catalog #: 27700
Size: 10 mg
$285
MW: 811.9 Da
CAS Registry #: 57576-44-0
Formula: C42H53NO15
Description:
Aclacinomycin A is a specific inhibitor of the 20S proteasome chymotrypsin-like activity and calpain activity. Aclarubicin acts by forming a stable complex with DNA. It was originally identified as an antitumor agent. Cell permeable.
Synonym(s):
Aclarubicin, Jaclacin
Purity:
≥95% by TLC.
Solubility:
Soluble in DMSO (30 mg/ml)
Format:
Orange powder
Storage / Stability:

Store at +4°C. Stable as supplied for up to 2 years when stored dessicated at +4°C. Store solutions at -20°C for up to 1 month.

Application(s):
Useful for as a potent, cell permeable proteasome inhibitor for drug discovery research.
Reference(s):
1. Figueiroda-Pereira, M.E., et al.; J. Biol. Chem. 1996, 271: 16455
Warning(s):
Protect from light. Protect from moisture. Avoid freeze/thaw cycles.
Scientific Category:
Protease
Product Type:
Inhibitors/Activators
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