p300 (KAT3B), His-GST-tags

Catalog #: 50071
Size: 50 µg
$425
Species: Human
Host Species: Sf9 insect cells
MW: 125 kDa
Genbank #: NM_001429
Tag(s): N-terminal His-GST-tags
a.a: 965–1810
Description:
Human E1A binding protein p300, also known as EP300, KAT3B, or RSTS2, GenBank Accession No. NM_001429, a.a. 965-1810, with N-terminal His-GST-tag, MW=125 kDa, expressed in Sf9 cells via a baculovirus expression system.
UniProt
Q09472
Synonym(s):
EP300, KAT3B, RSTS2, E1A binding protein, cbp
Specific Activity:
≥357 pmole/min/µg
Assay Conditions:
Assayed with the BPS Bioscience Fluorogenic p300 Assay Kit, Cat. # 50092, per manufacturer's instructions.
Formulation:
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 200 mM imidazole, and 20% glycerol.
Format:
Aqueous buffer solution
Storage / Stability:
>6 months at –80°C
Application(s):
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Reference(s):

1. Gui, Y., et al., Nat. Genet. 2011 Aug 7; 43(9) : 875 – 878.
2. Morin, R.D., et al., Nature. 2011 Jul 27; 476(7360) : 298 – 303.
3. Zhao, Z., et al., Brain Res. Bull. 2011 Oct 10; 86(3-4) : 189 – 194.

Product Specific Reference(s): 
1. Furdas, S.D. et al., Med. Chem. Commun. 2014; 5: 1856-1862.
2. Liao, D., et al., Cancer. Epigenetics. 2005; 1238: 539-548. 

Warning(s):
Avoid freeze/thaw cycles.
Scientific Category:
Acetyltransferase
Product Type:
Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.

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Product Datasheets

50071_Lot130221-G2.pdf