5X CD73 Assay Buffer

Catalog #: 74000
Size: 10 ml
$185
Background:

CD39 contributes to immune regulation through the hydrolysis of ATP to AMP in the rate limiting step of extracellular adenosine production. CD39 is expressed on the surface of multiple cells of the immune system including T-cells, Natural killer cells, B-cells, dendritic cells and macrophages. In addition, high levels of CD39 expression have been associated with the tumor microenvironment (TME). Research aimed at reducing immunosuppression by CD39 activity has resulted in the study of a small molecule inhibitor, POM1, and multiple anti-CD39 antibodies selected for blocking enzymatic activity or decreasing CD39 expression. 

Description:
The 5X CD73 Assay Buffer is optimized for assaying CD73. This buffer is designed for BPS Bioscience's colorimetric assays (cat# 72055 and cat# 72058).
Supplied As:
Tris-buffered solution
Format:
Aqueous buffer solution
Storage / Stability:
-80°C. Avoid freeze/thaw cycles. At least 12 months from date of receipt, when stored as directed.
Application(s):
Suitable for studying enzyme kinetics, and screening small molecular inhibitors of CD73 for HTS applications in drug discovery.
Scientific Category:
Immunotherapy
Product Type:
Assay Kit Component
Data shown is lot-specific. Contact us for specific information on other lots.

Quality Assurance